第三季的焦点重回到活跃于街头的Barksdale团伙，同时也将视角扩展到政治领域。此外，本季当中引入Hamsterdam这一新支线剧情，以探讨在部分人烟稀少的街区对非法毒品交易及卖淫的「事实性」合法化会有怎么样的潜在积极作用。这种做法在阿姆斯特丹和其他欧洲城市取得了积极成果，减少了市内的街头犯罪。这些都是对早先情节的延续。
CBS已续订《犯罪心理：穿越国界》第二季。
《犯罪心理：穿越国界 Criminal Minds: Beyond Borders》为《犯罪心理》的衍生剧，主要围绕FBI探员如何帮助国外居住的美国公民解决问题而展开。Gary Sinise：饰演Jack Garrett，在FBI待了20年，刚刚被指派负责这个部门。Tyler James Williams：饰演队中的技术分析员Monty，是个讨喜而又聪明的角色，平常在家工作，他对陷入困境的家庭以事无巨细的方式处理，协助队伍找到被遗留的线索，以及找到远在海外的真凶。Daniel Henney：Matt Simmons，不仅是一位在国外长大的军人还是一个居家好男人，喜欢探索和融入不同的文化，最重要的是他的侧写能力对整个团队致为关键。
Small Town, Big Story has started filming on location in Ireland under a UK Equity contract and follows goings-on in Drumbán, a rural village of rattled misfits. When a major Hollywood production rolls into town, a spotlight is thrown on a secret that has been kept hidden since the eve of the Millennium. Hendricks (Mad Men) is playing Wendy Patterson, a local girl done good as a hot-shot television producer, who returns to her hometown from LA with the Hollywood production in tow, while House of the Dragon’s Considine is local doctor and pillar of the community Seamus Proctor.
The detectives investigate a multiple homicide at a fast food restaurant; an addict gives his baby daughter to a drug dealer as collateral on an overdue loan; Internal Affairs reopens the Kirkendall case.
